ロバート ・ ケネラー のホームページへようこそ


「日本人の卓越した才能が古色蒼然とした事業に埋没してしまっているのは悲劇以外の何物でもない。」
"One of Japan's fundamental problems is that too much of its great human talent is locked up in old organizations doing old things."


(Bridging Islands から)


英語のページへ to my English pages


ロバート・ケネラー
Robert Kneller, J.D., M.D., M.P.H.
東京大学先端科学技術研究センター (RCAST) 教授


バイオ研究からのベンチャー立ち上げを支援



  •     medical needs analysis
  •     strategies for showing proof of concept
  •     strategies for obtaining funding
            (including linking to potential investors)
  •     intellectual property strategy
  •     strategies for obtaining regulatory (FDA/PMDA) approval
  •     strategies for engaging development collaborators
            (in universities, NGOs or private sector)
  •     negotiation of license contracts
Bridge to North American translational research and phase I/II clinical trial centers.
NRDDcover

Themes of Academic Work:

  • development of biomedical discoveries
  • startups and entrepreneurship
  • university-industry collaboration and technology transfer
  • intellectual property law
  • regulatory issues related to biomedical startups
  • relationship between education and innovation
  • international comparisons of the preceding, particularly between Japan and America

My research has focused on startups, entrepreneurship, intellectual property, university-industry technology transfer, and the importance of these factors for innovation and the development of biomedical discoveries for public benefit. Recent works include a survey of company perspectives on research collaborations with universities (PLOS ONE, 2014), a study of the origins of all the new drugs approved by the US FDA 1998-2007 which shows the importance of new companies for the discovery of innovative pharmaceuticals (Nature Reviews Drug Discovery, 2010) and an analysis of the Japanese and American environments for science-based entrepreneurship and the importance of science-based startups for innovation (Bridging Islands, Oxford 2007). Following a sabbatical in Stanford Medical School (2010-11) to better understand the support systems for science-based entrepreneurship in North America and how Japanese entrepreneurs can link to these systems, the focus of my work has shifted to (1) ways to foster the growth of startups based upon Japanese discoveries, particularly ways to help such startups to grow by developing international ties, and (2) ways to encourage inventions in Japanese universities to meet important health needs (invent for health).

I am board certified in General Preventive Medicine having completed my residency and public health studies in Johns Hopkins University. My MD is from Mayo Medical School (1984). I have a JD from Harvard Law School (1980). I graduated from Swarthmore College in 1975 with a major in physics and minor in economics. From 1988 to 1997 I worked in the US National Institutes of Health, first as a cancer epidemiologist, then in science policy, and finally at the coordinator for clinical cooperative R&D agreements with industry to develop NIH cancer drugs. I have worked in China on epidemiology studies and in clinical medicine and public health.

略歴

大学からの研究成果を開発するためのベンチャー起業、アントレプレナーシップ、知的財産管理および産学連携に焦点を当てた研究を行なっています。特に、バイオメディカル分野における大学からの研究成果の開発のためにこれらがどのように影響しているかを分析しています。これまでに出版された主なものとしては、バイオ分野におけるアントレプレナーシップを取り巻く環境の日米比較分析を行い、イノベーションのためのスタートアップの重要性を示した著書 (Bridging Islands, Oxford)、1998-2007年にFDAによって承認された新薬に関するデータを基に詳細な分析を行ない、新作用機序を持つ革新的新薬の開発におけるバイオベンチャーの貢献を明らかにした論文 (Nature Reviews Drug Discovery)、大学からの研究成果の商業化における民間との共同研究の役割の国際比較を行ない、企業が排他的な知的財産権を持つことが重要な場合もあれば、害を与える可能性もあることを示した論文 (PLOS ONE)があります。

バイオベンチャーは、他分野のベンチャー企業とは一線を画する複雑な構造を有し、商品化に至る過程で医薬品や医薬機器が国に承認される長期的なプロセスを含みます。これは、長期にわたる多大な資本が要求されることを意味し、それぞれの研究成果に最適な知的財産管理と承認プロセスに対する緻密な戦略が必要です。本研究室では、特にこのプロセスに対する有効な国際戦略を模索し、海外にネットワークを持つことで強力な競争力をもつ開発体制を構築する道を探っています。

Bridging Islands

オックスフォード出版のページはこちら

Amazon.com,       Amazon.co.jp


言語
英語、日本語、中国語、フランス語、ロシア語
kneller

Links to

  1. 履歴書(英語)

  2. その他

  3. 新聞記事など

  4. 東京大学先端科学技術研究センターのオフィシャル紹介ページ

Major Publications

  1. Robert Kneller, Marcel Mongeon, Jeff Cope, Cathy Garner, Philip Ternouth. 2014. Industry-university collaborations in Canada, Japan, the UK and USA - with emphasis on publication freedom and managing the intellectual property lock-up problem. PLOS ONE 9 (3) (e90302). [link to article]


  2. Kneller, Robert. 2013. Commercializing promising but dormant Japanese industry-university joint discoveries via independent, venture capital funded spin-offs. In Hishida, K (Ed.). Fulfilling the Promise of Technology Transfer: Fostering Innovation for the Benefit of Society. Springer. Pp 23-33.
    [link to chapter (PDF file)]


  3. Kneller, Robert. 2013. Umemura, The Japanese Pharmaceutical Industry: Its Evolution and Current Challenges (Review). Journal of Japanese Studies 39 (no. 1, winter 2013) 235-240.
    [link to review (PDF file)]


  4. ロバート・ケネラー 「イノベーションにおけるベンチャー企業の役割―アントレプレナーシップの環境改善に向けて―」 渡部俊也編 イノベーションシステムとしての大学と人材 (東京大学知的資産経営総括寄付講座シリーズ、第3巻、第3章) 白桃書房 (2011) 173-200 
    [link to bilingual version (PDF file)]


  5. Kneller, Robert. 2011. Invention Management in Japanese Universities and its Implications for Innovation: Insights from the University of Tokyo. In Wong, PK (ed). Academic Entrepreneurship in Asia: The Role and Impact of Universities in National Innovation Systems. Cheltenham UK: Elgar 69-85.
    [link to near-final chapter (PDF file)]


  6. Kneller, Robert. 2010. Importance of new companies for drug discovery: origins of a decade of new drugs. Nature Reviews Drug Discovery 9 (November) 867-882.
    [link to: main text, corrections to final (PDF files)]
    [link to main data table (xlsx file)]
    [links to other supplementary information: methodology notes, notes on particular drugs, broad topic notes,(PDF files)]

    [MSA Partnersが上記論文の書評を週報に掲載しています。新薬はどこから来たのか?イノベーション原動力としての大学役割 (PDF file)]


  7. Kneller, Robert. 2010. The changing governance of Japanese public science. In R. Whitley, J. Glaser & L. Engvall (eds), Reconfiguring Knowledge Production: Changing Authority Relations in the Sciences and Their Consequences for Intellectual Innovation, Oxford: Oxford U. Press. pp 110-145.
    (This chapter documents the high degree of concentration of R&D funding in just a few Japanese universities and examines its causes and possible consequences. Included is an analysis of the various types of funding and their allocation mechanisms.)
    [link to near-final chapter (PDF file)]


  8. ロバート・ケネラー・首藤 佐智子 大学共同研究における企業のプリエンプションの健全性を問う―ベンチャーを育む研究環境こそが真の科学を生み出す「Large companies’ preemption of university inventions by joint research is strangling Japanese entrepreneurship and contributing to the degradation of university science」日本知財学会誌 第5巻第2号(2008)
    [link to bilingual final version (PDF file)]


  9. Kneller, Robert. 2007. Bridging Islands: Venture Companies and the Future of Japanese and American Industry. Oxford University Press.
    (This book compares the environment for R&D-based startups in Japan and America and their importance for early stage innovation.)
    [publisher's summary]       Amazon.com,       Amazon.co.jp
    Links to selected chapters (PDF files):
    Preface and Contents,
    Chapter 1: Two Worlds of Innovation
    Chapter 3: University-Industry Relations
    Chapter 6: Ameoeba Innovation: The Alternative to Startups
    Chapter 7: Innovation Across Time and Space: Advantage New Companies


  10. Kneller, Robert. 2007. Prospective and retrospective evaluation systems in context: insights from Japan. In Whitley, Richard & Glaser, Jochen (eds.), Changing Governance of the Sciences: the Advent of Research Evaluation Systems (Sociology of the Sciences Yearbook). Springer: Dordrecht, Netherlands.
    (This chapter describes peer review of research funding in Japanese universities.)
    [link to: front pages, complete late draft] (PDF files)


  11. Kneller, Robert. 2007. The beginning of university entrepreneurship in Japan: TLOs and bioventures lead the way. Journal of Technology Transfer 32 (no.4, August) 435-456.
    (This article describes the post-2003 Japanese system of university-industry technology transfer and its implications for entrepreneurial startups.)
    [link to article (PDF file)]


  12. Kneller, Robert. 2006. Japan's new technology transfer system and the preemption of university discoveries by sponsored research and co-inventorship. Journal of the Association of University Technology Managers 18 (no. 1, summer 2006) 15-35.
    Republished with permission in Industry and Higher Education 21 (no.3, June 2007)
    [link to article (PDF file)]


  13. Kneller, Robert. 2005. Correspondence: The origins of new drugs (in 2 parts). Nature Biotechnology 23 (5&6) (May & June 2005)
    [link to articles: May, June] (PDF files)


  14. Kneller, Robert. 2003. Autarkic drug discovery in Japanese pharmaceutical companies: Insights into national differences in industrial innovation. Research Policy Vol. 32: 1805-1827.
    [link to: front page, complete late draft] (PDF files)


  15. Kneller, Robert. 2003. University-industry cooperation and technology transfer in Japan compared with the US: another reason for Japan's economic malaise? University of Pennsylvania Journal of International Economic Law Vol. 24(2) pp. 329-449. (summer).
    (This article describes how university-industry cooperation occurred in Japan prior to the incorporation of universities in 2004, and the associated legal framework.)
    [link to article (PDF file)]

  16. ロバート・ケネラー 知的財産制度とイノベーション 後藤 晃・長岡 貞男 (編) 産学連携制度の日米比較(第2章)(2003)(上記の日本語版)
    [link to late draft (PDF file)]


最近の発表

  1. 研究成果商業化のために米国・シリコンバレー活用を考える「Starting Companies in America to Commercialize Japanese Discoveries」 東京大学知的資産経営研究プロジェクト・新ビジネス塾 2012年2月14日
    [link to bilingual PPT)]

  2. 日本の大学とシリコンバレーをつなぐために「Linking Japanese University Science to Silicon Valley (or other overseas entrepreneurial regions)」. 第84回日本生化学会大会、セッション 4B 13: バイオ・イノベーションにかかる知的財産とアカデミック研究. 京都 2011年9月24日
    [link to PPT)]

  3. University IP management and science-based entrepreneurship in Japan--impact on innovation and questions for America , 17 June 2011, Office of Technology Licensing, Stanford University.
    [link to PPT)]

  4. 大学の特許管理は企業との連携にどのような影響を与えたか、日米比較からの考際「University Technology Management and its Impact on Relations with Industry: A comparative Japan-US perspective」。東京大学知的資産経営総括寄附講座公開セミナー、第4回2009年6月30日
    [link to English PPT)] [日本語のPPT)]

  5. The Relevance for Developing Economies of Technology Transfer from Universities and Government Research Institutes. 25 June 2009 presentation to the Asian Productivity Organization's Multi-country Study Mission on Management of Technology (in Tokyo).
    [link to PPT)]

SAKURA

Mt.Fuji sunset final


〒153-8904 東京都目黒区駒場4-6-1 東京大学先端科学技術研究センター
電話 +81-3-5452-5271  ファクス+81-3-5452-5376  メール kneller << >> tt.rcast.u-tokyo.ac.jp